Cell Line Development
Cell Line Development Services
Intellective Bio provides end-to-end cell line development solutions, from gene to GMP Working Cell Bank, to accelerate clients’ biotherapeutic programs from early-stage R&D to commercial production.Leveraging advanced vector construction, high-throughput screening platforms, and extensive expertise enable us to deliver high-yield, stable, and regulatory-compliant cell lines.
High-Performance CHO-K1-Based
Cell Line Development Platform
With over five years of experience in mammalian antibody development, we possess proprietary host cells, vectors, and culture media capable of supporting cell line development for a wide range of molecular types. Our diversified screening strategies accommodate varying IND submission timelines, supporting IND package submission in as fast as 9 months. To date, Intellective Biologics has successfully developed over 100 projects, with more than 20 projects currently in clinical trials—demonstrating the robustness of our screening system.
Cell Line Development
01
Vector
Construction
02
Cell
Transfection
03
Pool/Minipool Screening
04
Pool/Minipool Fed-Batch Evaluation
05
Pool/Minipool Clonal Derivation
06
Plate-Based Screening
07
Clone Fed-Batch Evaluation
08
PCB Banking and Stability Assessment
Flexible Timelines
Intellective’s latest "Fast-to-IND" service provides an IND-enabling data package within 9 months and a ready-to-use cell bank within 3 months. We tailor the technical scope and timeline according to project needs. As illustrated, our process—starting from host cell transfection—can deliver sequence-to-Master Cell Bank (MCB) construction in as little as 3 months. We support IND development timelines ranging from 9 to 14 months.
Standard Timeline(Months)
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Cell Line Development
MCB Cell Bank Stability
Upstream Process Development
Downstream Process Development
15 L Pool Material
FD 1st Screening
FD 2nd Screening
Analysis Methods Development and Qualification
MCB
WCB
Non-GMP lot
DP
Stability Study(3M)
Testing
GMP lot
DP
IND Dossier
Contact Info
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