Drug
With a strong track record of high batch success rates, Intellective Bio ensures superior product quality and safety, enabling a seamless transition from clinical to commercial manufacturing. Our drug substance production facilities are equipped with bioreactors ranging from 200 L to 6,000 L, available in both single-use and stainless-steel configurations to flexibly meet various production needs across different scales and stages.
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DS7 DS8 DS11 DS12 DS15(ADC) DS16 DS7 is equipped with two DS production lines, each featuring four 6,000-liters stainless steel bioreactors as its core highlight, and offers a flexibly adjustable production scale ranging from 2,000 liters to 6,000 liters. Through the organic integration of a Distributed Control System (DCS), a process monitoring and data acquisition system (SCADA), the production lines achieve a high level of automated monitoring and control.
24 kL
×46,000 L Stainless steel
Installed capacity : 113.4 kLIntellective Bio has configured a 2,000-liter single-use bioreactor (SUS) production line, which is specially designed to meet the production needs of both clinical-stage and commercial-scale manufacturing. Compared with the 6,000-liter stainless steel production line, this line offers higher flexibility and turnaround efficiency, and can quickly adapt to the production arrangements of multiple projects and product varieties.
7kL
×32,000 L Single Use System
×2500 L Single Use System
Installed capacity : 113.4 kLDS11 further enhance the company’s DS manufacturing capacity and accelerate the R&D and production processes of diverse biopharmaceuticals for global clients. Equipped with two DS production lines, this module enables flexible manufacturing at scales ranging from 2,000 L to 6,000 L, fully meeting clients’ end-to-end needs from clinical development to commercial production.
24 kL
×46,000 L Stainless steel
Installed capacity : 113.4 kLThe production line is equipped with stainless-steel reactors throughout and integrated with a centralized DeltaV automation control platform. The facility features a black-and-white segregation design and is equipped with a heat recovery system to enhance energy efficiency and reduce overall energy consumption.
24 kL
×46,000 L Stainless steel
Installed capacity : 113.4 kLDS15 is a dedicated conjugation manufacturing facility, providing clients with flexible production solutions ranging from early-stage development and pilot-scale manufacturing to commercial production.
In the purification stage, a single-use ultrafiltration system is adopted, where all product-contacting components are single-use assemblies, thus minimizing the risk of cross-contamination to the greatest extent.
Installed capacity : 113.4 kLDS16 is a pilot-scale production workshop designed to provide clients with a bridging platform spanning from process development to clinical sample preparation, facilitating the smooth transition of products from laboratory-scale research to commercial manufacturing.
It allows flexible adjustment of production scales according to project phases and process requirements, and supports the manufacturing of various types of antibodies and recombinant proteins.With its scalable process configurations and flexible equipment combinations, DS16 not only meets clients’ requirements for process verification and optimization, but also provides reliable technical support and data accumulation for future commercial manufacturing.
1.6 kL
×3200 L Single Use System
×1500 L Single Use System
×1500 L Stainless steel
Installed capacity: 113.4 kL -
DS4 DS5 Intellective Bio has established comprehensive manufacturing capabilities, with multiple Cytiva single-use bioreactors of 200 L and 2,000 L capacities installed across the facility.
4.4 kL
×22,000 L Single Use System
×2200 L Single Use System
Installed capacity: 113.4 kLIntellective Bio has established comprehensive manufacturing capabilities, featuring advanced vapor-phase liquid nitrogen storage tanks with automated supply and refill functions. The facility is equipped with three liquid nitrogen tanks for cell bank storage and seven Cytiva single-use bioreactors with capacities of 200 L and 2,000 L.
20.5 kL
×42,000 L Single Use System×26,000 L Single Use System×1500 L Single Use System
Installed capacity: 113.4 kL -
DS2 Intellective Bio operates an advanced fed-batch drug substance production line, integrated with Cytiva chromatography systems and depth filtration platforms from Millipore/Pall/Cobetter.
3.2 kL
×1200 L Single Use System
×2500 L Single Use System
×12,000 L Single Use System
Installed capacity : 113.4 kL
