Antibody Humanization

Human anti-mouse antibody response (HAMA) significantly affects the safety and efficacy of mouse-derived antibody therapies. Antibody humanization has become an important method to convert murine antibodies into safe and effective biopharmaceuticals. With industry-leading antibody engineering and recombinant antibody production platforms, we provide our partners with high-quality integrated services for antibody humanization and affinity maturity. Based on the principle of CDR transplantation and recovery mutation, our humanization platform, combined with bioinformatics and structural biology to assist design and optimization, can quickly and effectively weaken the immunogenicity of antibodies while maintaining high affinity, activity, stability and yield.