Downstream Process Development

Our Services

Intellective BIO has a dedicated and innovative downstream process technology platform with a full range of development capabilities, including purification process development, optimisation, scale-up and process characterisation.

Our technical experts have the expertise and industry experience to significantly improve product quality and batch yields, shorten project development times, and develop cost-effective processes for long-term commercialisation.

Development process

Why Us?

"Much"
- Experience in purification of many types of molecules, including antibodies (mAb, BsAb, TsAb, VHH, etc.), fusion proteins, coagulation factors and other recombinant proteins;
- Multiple original purification platforms, including multi-antibody purification platform, recombinant protein purification platform (including tagged and untagged proteins), acidic protein purification platform, vaccine purification platform, and high concentration ultrafiltration platform;
"Quick"
- High-throughput process development platform to fast-track DNA-to-IND to 4 months;
- Well-documented platforms, unique development, optimisation and characterisation strategies allow for a rapid commercialisation process;
"Good"
- Patented purification technology means to achieve SEC purity from 75% to 99%;
- Utilising several original purification platforms for difficult projects, significant reductions in impurities such as aggregates, fragments, charge isomers and HCP can be achieved;
"Save"
- By improving the process design and optimising the process parameters, the cumulative yield can be as high as 90%, which greatly enhances the product economics;
- Well-documented platforms, unique development, optimisation and characterisation strategies allow for a rapid commercialisation process;